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M94A2410.TXT
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Document 2410
DOCN M94A2410
TI Infants born from HIV+ mothers.
DT 9412
AU Rimoldi I; Avolio J; Arreseigor T; Provincial Ref. Center for AIDS, La
Plata, Argentina.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):310 (abstract no. PC0168). Unique
Identifier : AIDSLINE ICA10/94370165
AB OBJECTIVE: To describe and to evaluate results obtained in our
Laboratory from serum samples of infants born from seropositive mothers
in Buenos Aires, Argentina. METHODS: 18 month follow-up using
serological techniques: EIA or PA--WB and EIA(Ag)--HIV antigen
confirmation. Licensed kits were used. RESULTS: 489 serum samples of 306
infants born from HIV seropositive mothers were received from Jan. 1989
through Dec. 1993 (1989 = 32, 1990 = 43, 1991 = 66, 1992 = 88, 1993 =
77). 69 (22.5%) have completed the follow-up; 30 of them (43.5%)
remained seropositive, 32 (46.4%) seroreverted, and 7 (10.1%) were
undetermined (p-24 band was still present after long term follow-up). 52
infants are still under follow-up. 169 (55.4%) were lost and their
present status is unknown; 42 were HIV+ at first sample, presenting
clinical symptoms of AIDS while their mothers' HIV+ status were unknown;
31 were elder than 18 months, and 11 were under 12 months, being
serological diagnosis very difficult due to total or partial lose of HIV
specific antibody. CONCLUSION: 1) hard policies and social service are
needed for these infants' families to lead an adequate clinical and
serological follow-up. 2) Early detection of perinatal HIV acquired
infection is needed to establish the specific therapy as soon as
possible.
DE *AIDS Serodiagnosis Female Human HIV
Infections/DIAGNOSIS/*TRANSMISSION *HIV Seropositivity Infant Infant,
Newborn Pregnancy *Pregnancy Complications, Infectious MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).